Malignant Hyperthermia in Belgium: 35 years of practice-led research

As of 1986 a laboratory for the diagnosis Malignant Hyperthermia (MH) was established at University Antwerp which since then served as national reference this rare anesthetic complication. Our unit is an accredited lab within network European Group and thus has had chance to attain solid practical expertise in disorder, well collaborate several multicentre studies on MH. The present review summarizes what collaborative international research taught us about MH over last 3,5 decades, covers evolving insights such topics pathophysiology, clinical presentation, treatment, anesthesia patients with increased risk developing MH, molecular genetics, diagnostic work-up relationship other myopathies.